Monday, October 6, 2014

Easier to track hidden toxic algae – forskning.se

Cyanobacteria, which is the more correct name for the unhealthy organisms is rapidly increasing worldwide as a result of eutrophication and global warming.

Early detection can save lives and make cleaning operations easier and more efficient, particularly in hot environments such as Africa, Australia and the southern United States where they draw their drinking water from ponds and streams where algae blooms are becoming more common. The technology is portable, inexpensive and quick read.

Even in Sweden believed moose, dogs, birds and animals have become sick and sometimes died after being received in themselves the dangerous toxins.

Behind the technology is Lesedi Lebogang, PhD in Biotechnology at Lund University. She has just brought out a treatise in which technology is presented. She came to Sweden from the Botswana International University of Science and Technology in Palapye.

– In Botswana cyanobacteria is a real problem. There are several reports of boskapsdöd Botswana because of toxic algae in recent years, said Lesedi Lebogang.

To Lesedi Lebogang ended up in Lund is because this is a biosensor Bo Mattiasson and Martin Hedstrom, both researchers in biotechnology, has invented. The method is thus an adaptation of this basic technology, which aims to track the extremely small concentrations in liquids, on which Lesedi Lebogang succeeded in adding the antibody chemicals that tracks cyanobakteriens toxins.

When cyanobacterium crack emits a variety of toxins that antibodies can react to the result that the sensor reacts.

– Integrating analysis system in a real situation where the real hard nut to crack, says Lesedi Lebogang.

Lesedi Lebogang plan to continue the research at home in Botswana. The technology is patented in Sweden and will be commercially available in about a year.

The basic technology is simplified version of the sensor picks up small biochemical signals which are then amplified and converted into measurable electrical signals.

Another adaptation is Early HIV diagnosis, already a few days up to a week after infection. The FDA is here with and evaluating the technology. While current methods primarily measure antibodies this method can measure extremely low levels of virus marker protein p24, which sits on the virus surface and released into the bloodstream.

FACT
Link to Lesedi Lebogangs thesis “ Biosensor-based Methods for Detection of Microcystins as Early Warning Systems ” http://www.lu.se/lup/publication/4610658link to , opens in new window

Scientific Publishing” Development of a real-time capacitive biosensor for cyclic peptides based on cyanotoxic Adda-specific antibodies “in Analytica Chimica Acta http://www.sciencedirect.com/science/article/pii / S000326701400350X external link, opens in new window

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