Thursday, October 20, 2016

Unexpected discovery: the Supermaterial kills bacteria (New Technology)

the Forests of tiny, sharp grafenflak can kill pathogenic bacteria. The researchers at Chalmers university of technology and the medical technology company Wellspect detection.

Can an area of the graph to prevent bacteria from growing on a catheter and in this way reduce the risk of urinary tract infection? It was the starting point when it evalute medtech company Wellspect last year began to explore their antibacterial properties, along with researchers at Chalmers.

today, a year and countless tests later, their research resulted in new findings.

– When we manufacture grafenytor in the form of a small forest of razor-sharp grafenflak, the material is an effective bakteriedödare, ” says Ivan Mijakovic, professor of systemmikrobiologi and leader of the life sciences and technology at Chalmers university of technology.

Tests on the most common bacteria behind the urinary tract infection shows that 70 to 80% of the bacteria dying on the sharp grafenytan. E-coli belongs to them.

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For Wellspect can discovery lead to a new way to ensure that people who use any of the company’s incontinence products are not affected by infections.

– It seems that the graph in the vertical form punkterar the bacteria’s cell membranes. Next, drag the graphene to the membranmolekylernas fat ends of the earth. As a result, the membrane collapses and cells die, ” says Martin Lovmar, researcher and project coordinator at Wellspect.

Affected human cells in the same way?

” we still don’t know, but in order to have the effect of requiring the direct contact with the cells. Perhaps one should not use the material in catheters, but instead on some incontinence products that have parts that are outside the body and re-used.

What are the next steps?

” We are going ahead with kontrollexperiment in parallel with developing production methods that makes it possible to produce larger quantities at reasonable price. The latter is crucial for business.

But the graph in general is not any bakteriedödare. Usually manufactured material as a flat surface. In this form, the graph is harmless to the bacteria, say the researchers. However, they have discovered that the material seems to react on the bacteria.

– It seems that the flat surfaces of the graph signal when a pathogenic bacterium found in the vicinity. Maybe it can be used for sensors that can warn of bacteria before they cause symptoms, ” says Martin Lovmar.

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Parallellspåret shall now be further explored by the three post-doc.

it is Possible to obtain signals that can distinguish between different types of bacteria? Is this a signal that only goes to get in the lab, or you can also get it from a device in the body, are some of the questions that seek answers.

technically, the project has so far not been any challenge, mean Chalmersprofessorn Ivan Mijakovic.

” the Challenge was to understand. We had no idea how the graphene interacts with the bacteria. The literature in the field was confusing. Now, we know that we can control how graphene interacts with the bacteria by the geometry, ” he says.

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